PRCP purified MaxPab rabbit polyclonal antibody (D01P)
产品名称： PRCP purified MaxPab rabbit polyclonal antibody (D01P)
英文名称： PRCP purified MaxPab rabbit polyclonal antibody (D01P)
产品编号： H00005547-D01P
产品价格： null
产品产地： 台湾
品牌商标： Abnova
更新时间： null
使用范围：
亚诺法生技股份有限公司（Abnova)
- 联系人 :
- 地址 : 台湾台北市内湖区洲子街 108 号 9 楼
- 邮编 : 11493
- 所在区域 : 台湾
- 电话 : +886-920**1152 点击查看
- 传真 : 点击查看
- 邮箱 : sales@abnova.com.tw
- Specification
- Product Description:
- Rabbit polyclonal antibody raised against a full-length human PRCP protein.
- Immunogen:
- PRCP (NP_005031.1, 1 a.a. ~ 496 a.a) full-length human protein.
- Sequence:
- MGRRALLLLLLSFLAPWATIALRPALRALGSLHLPTNPTSLPAVAKNYSVLYFQQKVDHFGFNTVKTFNQRYLVADKYWKKNGGSILFYTGNEGDIIWFCNNTGFMWDVAEELKAMLVFAEHRYYGESLPFGDNSFKDSRHLNFLTSEQALADFAELIKHLKRTIPGAENQPVIAIGGSYGGMLAAWFRMKYPHMVVGALAASAPIWQFEDLVPCGVFMKIVTTDFRKSGPHCSESIHRSWDAINRLSNTGSGLQWLTGALHLCSPLTSQDIQHLKDWISETWVNLAMVDYPYASNFLQPLPAWPIKVVCQYLKNPNVSDSLLLQNIFQALNVYYNYSGQVKCLNISETATSSLGTLGWSYQACTEVVMPFCTNGVDDMFEPHSWNLKELSDDCFQQWGVRPRPSWITTMYGGKNISSHTNIVFSNGELDPWSGGGVTKDITDTLVAVTISEGAHHLDLRTKNALDPMSVLLARSLEVRHMKNWIRDFYDSAGKQH
- Host:
- Rabbit
- Reactivity:
- Human
- Storage Buffer:
- In 1x PBS, pH 7.2
- Storage Instruction:
- Store at -20°C or lower. Aliquot to avoid repeated freezing and thawing.
- Quality Control Testing:
- Antibody reactive against mammalian transfected lysate.
- MSDS:
Download
- Applications
- Western Blot (Transfected lysate)
- Western Blot analysis of PRCP expression in transfected 293T cell line (H00005547-T02) by PRCP MaxPab polyclonal antibody.
Lane 1: PRCP transfected lysate(55.80 KDa).
Lane 2: Non-transfected lysate. - Protocol Download
- Entrez GeneID:
- 5547
- GeneBank Accession#:
- NM_005040
- Protein Accession#:
- NP_005031.1
- Gene Name:
- PRCP
- Gene Alias:
- HUMPCP,MGC2202,PCP
- Gene Description:
- prolylcarboxypeptidase (angiotensinase C)
- Omim ID:
- 176785
- Gene Ontology:
- Hyperlink
- Gene Summary:
- The protein encoded by this gene is a lysosomal prolylcarboxypeptidase, which cleaves C-terminal amino acids linked to proline in peptides such as angiotension II, III and des-Arg9-bradykinin. The cleavage occurs at acidic pH, but the enzyme activity is retained with some substrates at neutral pH. This enzyme has been shown to be an activator of the cell matrix-associated prekallikrein. The importance of angiotension II, one of the substrates of this enzyme, in regulating blood pressure and electrolyte balance suggests that this gene may be related to essential hypertension. Alternatively spliced transcript variants encoding distinct isoforms have been observed. [provided by RefSeq
- Other Designations:
- angiotensinase C,lysosomal Pro-x carboxypeptidase,lysosomal carboxypeptidase C,proline carboxypeptidase,prolylcarboxypeptidase,prolylcarboxypeptidase isoform 1 preproprotein