PPP1R8 monoclonal antibody (M05), clone 4B5
产品名称： PPP1R8 monoclonal antibody (M05), clone 4B5
英文名称： PPP1R8 monoclonal antibody (M05), clone 4B5
产品编号： H00005511-M05
产品价格： null
产品产地： 台湾
品牌商标： Abnova
更新时间： null
使用范围：
亚诺法生技股份有限公司（Abnova)
- 联系人 :
- 地址 : 台湾台北市内湖区洲子街 108 号 9 楼
- 邮编 : 11493
- 所在区域 : 台湾
- 电话 : +886-920**1152 点击查看
- 传真 : 点击查看
- 邮箱 : sales@abnova.com.tw
- Specification
- Product Description:
- Mouse monoclonal antibody raised against a partial recombinant PPP1R8.
- Immunogen:
- PPP1R8 (NP_002704.1, 28 a.a. ~ 127 a.a) partial recombinant protein with GST tag. MW of the GST tag alone is 26 KDa.
- Sequence:
- RRMQNFAFSGGLYGGLPPTHSEAGSQPHGIHGTALIGGLPMPYPNLAPDVDLTPVVPSAVNMNPAPNPAVYNPEAVNEPKKKKYAKEAWPGKKPTPSLLI
- Host:
- Mouse
- Reactivity:
- Human
- Isotype:
- IgG2a Kappa
- Storage Buffer:
- In 1x PBS, pH 7.2
- Storage Instruction:
- Store at -20°C or lower. Aliquot to avoid repeated freezing and thawing.
- Quality Control Testing:
- Antibody Reactive Against Recombinant Protein.
Western Blot detection against Immunogen (36.74 KDa) .
- MSDS:
Download
- Applications
- Western Blot (Transfected lysate)
- Western Blot analysis of PPP1R8 expression in transfected 293T cell line by PPP1R8 monoclonal antibody (M05), clone 4B5.
Lane 1: PPP1R8 transfected lysate (Predicted MW: 38.5 KDa).
Lane 2: Non-transfected lysate. - Protocol Download
- Western Blot (Recombinant protein)
- Protocol Download
- Immunoprecipitation
- Immunoprecipitation of PPP1R8 transfected lysate using anti-PPP1R8 monoclonal antibody and Protein A Magnetic Bead (U0007), and immunoblotted with PPP1R8 monoclonal antibody.
- Protocol Download
- Sandwich ELISA (Recombinant protein)
- Detection limit for recombinant GST tagged PPP1R8 is approximately 3ng/ml as a capture antibody.
- Protocol Download
- Entrez GeneID:
- 5511
- GeneBank Accession#:
- NM_002713
- Protein Accession#:
- NP_002704.1
- Gene Name:
- PPP1R8
- Gene Alias:
- ARD-1,ARD1,NIPP-1,NIPP1,PRO2047
- Gene Description:
- protein phosphatase 1, regulatory (inhibitor) subunit 8
- Omim ID:
- 602636
- Gene Ontology:
- Hyperlink
- Gene Summary:
- This gene, through alternative splicing, encodes three different isoforms. Two of the protein isoforms encoded by this gene are specific inhibitors of type 1 serine/threonine protein phosphatases and can bind but not cleave RNA. The third protein isoform lacks the phosphatase inhibitory function but is a single-strand endoribonuclease comparable to RNase E of E. coli. This isoform requires magnesium for its function and cleaves specific sites in A+U-rich regions of RNA. [provided by RefSeq
- Other Designations:
- OTTHUMP00000003847,OTTHUMP00000003848,OTTHUMP00000003849,OTTHUMP00000044938,RNase E,activator of RNA decay,nuclear inhibitor of protein phosphatase-1,nuclear subunit of PP-1,protein phosphatase 1 regulatory inhibitor subunit 8,protein phosphatase 1 regula