Anti-ERCC1 Monoclonal Antibody-抗体-抗体-生物在线

Anti-ERCC1 Monoclonal Antibody

商家询价

产品名称： Anti-ERCC1 Monoclonal Antibody

英文名称： Anti-ERCC1 Monoclonal Antibody

产品编号： K000149M

产品价格： null

产品产地：北京

品牌商标： Solarbio

更新时间： 2025-04-16T13:06:03

使用范围： WB

北京索莱宝科技有限公司

联系人 : 索莱宝-龚思雨
地址 : 北京市通州区中关村科技园区通州园金桥科技产业基地景盛南四街15号85A三层
邮编 : 101102
所在区域 : 北京
电话 : 178****1073 点击查看
传真 : 点击查看
邮箱 : 3193328036@qq.com
二维码 : 点击查看

进入展台

产品详情

Anti-ERCC1 Monoclonal Antibody
品牌：solarbio | 货号：K000149M
 
 
英文名称 Anti-ERCC1 Monoclonal Antibody
宿主 Mouse
别名 COFS4;RAD10;UV20
应用 WB
稀释比例 WB 1:1000.
交叉反应 Human
蛋白分子量 33kDa
Gene ID 2067
保存 Store at -20°C. Avoid freeze / thaw cycles.
储存液 Buffer: PBS with 0.02% sodium azide, 50% glycerol, pH7.3.
纯化方法 Affinity purification
亚型 IgG2b
免疫原 Purified recombinant human ERCC1 protein fragments expressed in E.coli.
性状 液体
Public Immunogen Range Purified recombinant human ERCC1 protein fragments expressed in E.coli.
Subcellular Locations Cytoplasm Nucleus
Swiss Prot P07992
克隆号 7F6-2A10-E8
克隆类型 Monoclonal Antibody
背景资料 The product of this gene functions in the nucleotide excision repair pathway,and is required for the repair of DNA lesions such as those induced by UV light or formed by electrophilic compounds including cisplatin.The encoded protein forms a heterodimer with the XPF endonuclease (also known as ERCC4),and the heterodimeric endonuclease catalyzes the 5' incision in the process of excising the DNA lesion.The heterodimeric endonuclease is also involved in recombinational DNA repair and in the repair of inter-strand crosslinks.Mutations in this gene result in cerebrooculofacioskeletal syndrome,and polymorphisms that alter expression of this gene may play a role in carcinogenesis.Multiple transcript variants encoding different isoforms have been found for this gene.The last exon of this gene overlaps with the CD3e molecule,epsilon associated protein gene on the opposite strand.[provided by RefSeq,Oct 2009]

英文名称	Anti-ERCC1 Monoclonal Antibody
宿主	Mouse
别名	COFS4;RAD10;UV20
应用	WB
稀释比例	WB 1:1000.
交叉反应	Human
蛋白分子量	33kDa
Gene ID	2067
保存	Store at -20°C. Avoid freeze / thaw cycles.
储存液	Buffer: PBS with 0.02% sodium azide, 50% glycerol, pH7.3.
纯化方法	Affinity purification
亚型	IgG2b
免疫原	Purified recombinant human ERCC1 protein fragments expressed in E.coli.
性状	液体
Public Immunogen Range	Purified recombinant human ERCC1 protein fragments expressed in E.coli.
Subcellular Locations	Cytoplasm Nucleus
Swiss Prot	P07992
克隆号	7F6-2A10-E8
克隆类型	Monoclonal Antibody
背景资料	The product of this gene functions in the nucleotide excision repair pathway,and is required for the repair of DNA lesions such as those induced by UV light or formed by electrophilic compounds including cisplatin.The encoded protein forms a heterodimer with the XPF endonuclease (also known as ERCC4),and the heterodimeric endonuclease catalyzes the 5' incision in the process of excising the DNA lesion.The heterodimeric endonuclease is also involved in recombinational DNA repair and in the repair of inter-strand crosslinks.Mutations in this gene result in cerebrooculofacioskeletal syndrome,and polymorphisms that alter expression of this gene may play a role in carcinogenesis.Multiple transcript variants encoding different isoforms have been found for this gene.The last exon of this gene overlaps with the CD3e molecule,epsilon associated protein gene on the opposite strand.[provided by RefSeq,Oct 2009]