ABCC8 polyclonal antibody (A01)
产品名称: ABCC8 polyclonal antibody (A01)
英文名称: ABCC8 polyclonal antibody (A01)
产品编号: H00006833-A01
产品价格: null
产品产地: 台湾
品牌商标: Abnova
更新时间: null
使用范围:
亚诺法生技股份有限公司(Abnova)
- 联系人 :
- 地址 : 台湾台北市内湖区洲子街 108 号 9 楼
- 邮编 : 11493
- 所在区域 : 台湾
- 电话 : +886-920**1152 点击查看
- 传真 : 点击查看
- 邮箱 : sales@abnova.com.tw
- Specification
- Product Description:
- Mouse polyclonal antibody raised against a partial recombinant ABCC8.
- Immunogen:
- ABCC8 (NP_000343, 611 a.a. ~ 710 a.a) partial recombinant protein with GST tag.
- Sequence:
- SEFLSSAEIREEQCAPHEPTPQGPASKYQAVPLRVVNRKRPAREDCRGLTGPLQSLVPSADGDADNCCVQIMGGYFTWTPDGIPTLSNITIRIPRGQLTM
- Host:
- Mouse
- Reactivity:
- Human
- Storage Buffer:
- 50 % glycerol
- Storage Instruction:
- Store at -20°C or lower. Aliquot to avoid repeated freezing and thawing.
- Quality Control Testing:
- Antibody Reactive Against Recombinant Protein.
Western Blot detection against Immunogen (37.11 KDa) .
- MSDS:
- Download
- Application Image
- Western Blot (Recombinant protein)
- ELISA
- Entrez GeneID:
- 6833
- GeneBank Accession#:
- NM_000352
- Protein Accession#:
- NP_000343
- Gene Name:
- ABCC8
- Gene Alias:
- ABC36,HHF1,HI,HRINS,MRP8,PHHI,SUR,SUR1,TNDM2
- Gene Description:
- ATP-binding cassette, sub-family C (CFTR/MRP), member 8
- Gene Ontology:
- Hyperlink
- Gene Summary:
- The protein encoded by this gene is a member of the superfamily of ATP-binding cassette (ABC) transporters. ABC proteins transport various molecules across extra- and intra-cellular membranes. ABC genes are divided into seven distinct subfamilies (ABC1, MDR/TAP, MRP, ALD, OABP, GCN20, White). This protein is a member of the MRP subfamily which is involved in multi-drug resistance. This protein functions as a modulator of ATP-sensitive potassium channels and insulin release. Mutations and deficiencies in this protein have been observed in patients with hyperinsulinemic hypoglycemia of infancy, an autosomal recessive disorder of unregulated and high insulin secretion. Mutations have also been associated with non-insulin-dependent diabetes mellitus type II, an autosomal dominant disease of defective insulin secretion. Alternative splicing of this gene has been observed; however, the transcript variants have not been fully described. [provided by RefSeq
- Other Designations:
- ATP-binding cassette, sub-family C, member 8,sulfonylurea receptor (hyperinsulinemia)
- Gene Pathway
- Related Disease
- Adenocarcinoma
- Alzheimer Disease
- Alzheimer disease
- Atherosclerosis
- Cardiovascular Diseases
- Cerebrovascular Accident
- Chronic Disease
- Diabetes Complications
- Diabetes Mellitus
- Diabetes Mellitus, Type 1
- Diabetes Mellitus, Type 2
- Diabetes, Gestational
- Diabetic Angiopathies
- Disease Progression
- Drug Toxicity
- Edema
- Esophageal Neoplasms
- Genetic Predisposition to Disease
- Glucose Intolerance