FITC标记的FAM172A蛋白抗体
产品名称： FITC标记的FAM172A蛋白抗体
英文名称： Anti-FAM172A/FITC
产品编号： HZ-13772R-FITC
产品价格： null
产品产地： 中国/上海
品牌商标： HZbscience
更新时间： 2023-08-17T10:24:20
使用范围： ICC=1:50-200 IF=1:50-200
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Rabbit Anti-FAM172A/FITC Conjugated antibody
FITC标记的FAM172A蛋白抗体
| 英文名称 | Anti-FAM172A/FITC |
| 中文名称 | FITC标记的FAM172A蛋白抗体 |
| 别 名 | C5orf21; F172A_HUMAN; fam172a; Family with sequence similarity 172, member A; Protein FAM172A |
| 规格价格 | 100ul/2980元 购买 大包装/询价 |
| 说 明 书 | 100ul |
| 研究领域 | 肿瘤 细胞生物 |
| 抗体来源 | Rabbit |
| 克隆类型 | Polyclonal |
| 交叉反应 | Human, Mouse, Rat, Rabbit, |
| 产品应用 | ICC=1:50-200 IF=1:50-200 not yet tested in other applications. optimal dilutions/concentrations should be determined by the end user. |
| 分 子 量 | 131kDa |
| 性 状 | Lyophilized or Liquid |
| 浓 度 | 1mg/ml |
| 免 疫 原 | KLH conjugated synthetic peptide derived from human FAM172A |
| 亚 型 | IgG |
| 纯化方法 | affinity purified by Protein A |
| 储 存 液 | 0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glycerol. |
| 保存条件 | Store at -20 °C for one year. Avoid repeated freeze/thaw cycles. The lyophilized antibody is stable at room temperature for at least one month and for greater than a year when kept at -20°C. When reconstituted in sterile pH 7.4 0.01M PBS or diluent of antibody the antibody is stable for at least two weeks at 2-4 °C. |
| 产品介绍 | background: FAM172A is a 416 amino acid secreted protein belonging to the UPF0528 family and is encoded by a gene located on human chromosome 5. Chromosome 5 contains 181 million base pairs and comprises nearly 6% of the human genome. Chromosome 5 is associated with Cockayne syndrome through the ERCC8 gene and familial adenomatous polyposis through the adenomatous polyposis coli (APC) tumor suppressor gene. Treacher Collins syndrome is also chromosome 5-associated and is caused by insertions or deletions within the TCOF1 gene. Deletion of the p arm of chromosome 5 leads to Cri du chat syndrome, while deletion of the q arm or of chromosome 5 altogether is common in therapy-related acute myelogenous leukemias and myelodysplastic syndrome. Subcellular Location: Secreted. Similarity: Belongs to the UPF0528 family. Database links: Entrez Gene: 83989 Human Entrez Gene: 68675 Mouse Entrez Gene: 294606 Rat SwissProt: Q8WUF8 Human SwissProt: Q3TNH5 Mouse Unigene: 600086 Human Unigene: 343005 Mouse Unigene: 203242 Rat Important Note: This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications |
FAM172A是属于UPF0528家族的416个氨基酸分泌蛋白，由位于人类5号染色体上的基因编码。第5染色体包含1亿8100万个碱基对，并包含人类基因组的近6%。5号染色体通过ERCC8基因与Cockayne综合征相关，家族性腺瘤性息肉病通过APC抑癌基因与腺瘤性息肉病相关。Treacher Collins综合征也是5号染色体相关的，是由TCOF1基因内的插入或缺失引起的。5号染色体p臂缺失导致Cri du chat综合征，而q臂或5号染色体缺失在治疗相关的急性髓细胞白血病和骨髓增生异常综合征中很常见。