HSD17B1 monoclonal antibody (M03), clone 2E5
产品名称： HSD17B1 monoclonal antibody (M03), clone 2E5
英文名称： HSD17B1 monoclonal antibody (M03), clone 2E5
产品编号： H00003292-M03
产品价格： null
产品产地： 台湾
品牌商标： Abnova
更新时间： null
使用范围：
亚诺法生技股份有限公司（Abnova)
- 联系人 :
- 地址 : 台湾台北市内湖区洲子街 108 号 9 楼
- 邮编 : 11493
- 所在区域 : 台湾
- 电话 : +886-920**1152 点击查看
- 传真 : 点击查看
- 邮箱 : sales@abnova.com.tw
- Specification
- Product Description:
- Mouse monoclonal antibody raised against a partial recombinant HSD17B1.
- Immunogen:
- HSD17B1 (NP_000404, 189 a.a. ~ 285 a.a) partial recombinant protein with GST tag. MW of the GST tag alone is 26 KDa.
- Sequence:
- VHTAFMEKVLGSPEEVLDRTDIHTFHRFYQYLAHSKQVFREAAQNPEEVAEVFLTALRAPKPTLRYFTTERFLPLLRMRLDDPSGSNYVTAMHREVF
- Host:
- Mouse
- Reactivity:
- Human
- Isotype:
- IgG1 Kappa
- Storage Buffer:
- In 1x PBS, pH 7.2
- Storage Instruction:
- Store at -20°C or lower. Aliquot to avoid repeated freezing and thawing.
- Quality Control Testing:
- Antibody Reactive Against Recombinant Protein.
Western Blot detection against Immunogen (36.41 KDa) .
- MSDS:
Download
- Publication Reference
- 1.
- The role of estrogen-metabolizing enzymes and estrogen receptors in human epidermis.
Inoue T, Miki Y, Abe K, Hatori M, Hosaka M, Kariya Y, Kakuo S, Fujimura T, Hachiya A, Aiba S, Sasano H.Mol Cell Endocrinol. 2011 Jun 29. [Epub ahead of print]
- 2.
- Increased estrogen sulfatase (STS) and 17beta-hydroxysteroid dehydrogenase type 1(17beta-HSD1) following neoadjuvant aromatase inhibitor therapy in breast cancer patients.
Chanplakorn N, Chanplakorn P, Suzuki T, Ono K, Chan MS, Miki Y, Saji S, Ueno T, Toi M, Sasano H.Breast Cancer Res Treat. 2010 Apr;120(3):639-48. Epub 2010 Feb 12.
- Applications
- Western Blot (Cell lysate)
- HSD17B1 monoclonal antibody (M03), clone 2E5 Western Blot analysis of HSD17B1 expression in Jurkat ( Cat # L017V1 ).
- Protocol Download
- Western Blot (Recombinant protein)
- Protocol Download
- Immunohistochemistry (Formalin/PFA-fixed paraffin-embedded sections)
enlarge this image- Immunoperoxidase of monoclonal antibody to HSD17B1 on formalin-fixed paraffin-embedded human small Intestine. [antibody concentration 3 ug/ml]
- Protocol Download
- Sandwich ELISA (Recombinant protein)
- Detection limit for recombinant GST tagged HSD17B1 is 0.03 ng/ml as a capture antibody.
- Protocol Download
- Entrez GeneID:
- 3292
- GeneBank Accession#:
- NM_000413
- Protein Accession#:
- NP_000404
- Gene Name:
- HSD17B1
- Gene Alias:
- EDH17B2,EDHB17,HSD17,MGC138140,SDR28C1
- Gene Description:
- hydroxysteroid (17-beta) dehydrogenase 1
- Omim ID:
- 109684
- Gene Ontology:
- Hyperlink
- Other Designations:
- Estradiol 17-beta-dehydrogenase-1,hydroxysteroid (17-beta) dehydrogenase 1 isoform,short chain dehydrogenase/reductase family 28CE, member 1
- Gene Pathway
- Related Disease
- Adenocarcinoma
- Appetite
- Breast cancer
- Breast Neoplasms
- Carcinoma
- Carcinoma, Ductal, Breast
- Carcinoma, Non-Small-Cell Lung
- Cryptorchidism
- Diabetes Mellitus
- Edema
- Endometrial Neoplasms
- Endometriosis
- Esophageal Neoplasms
- Fibroadenoma
- Fibrocystic Breast Disease
- Genetic Predisposition to Disease
- Insulin Resistance
- Lung Neoplasms
- Lymphoma, Non-Hodgkin