MBP (phospho T232) polyclonal antibody
产品名称： MBP (phospho T232) polyclonal antibody
英文名称： MBP (phospho T232) polyclonal antibody
产品编号： PAB8177
产品价格： null
产品产地： 台湾
品牌商标： Abnova
更新时间： null
使用范围：
亚诺法生技股份有限公司（Abnova)
- 联系人 :
- 地址 : 台湾台北市内湖区洲子街 108 号 9 楼
- 邮编 : 11493
- 所在区域 : 台湾
- 电话 : +886-920**1152 点击查看
- 传真 : 点击查看
- 邮箱 : sales@abnova.com.tw
- Specification
- Product Description:
- Rabbit polyclonal antibody raised against synthetic phosphopeptide of MBP.
- Immunogen:
- Synthetic phosphopeptide (conjugated with KLH) corresponding to residues surrounding T232 of human MBP.
- Host:
- Rabbit
- Reactivity:
- Human
- Form:
- Liquid
- Purification:
- Protein A purification
- Storage Buffer:
- In PBS (0.09% sodium azide)
- Storage Instruction:
- Store at 4°C. For long term storage store at -20°C.
Aliquot to avoid repeated freezing and thawing.
- Recommend Usage:
- ELISA (1:1000)
Dot Blot (1:500)
The optimal working dilution should be determined by the end user.
- Note:
- This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
- Publication Reference
- 1.
- Myelin-reactive type B T cells and T cells specific for low-affinity MHC-binding myelin peptides escape tolerance in HLA-DR transgenic mice.
Kawamura K, McLaughlin KA, Weissert R, Forsthuber TG.J Immunol. 2008 Sep 1;181(5):3202-11.
- 2.
- Interaction between the C-terminal region of human myelin basic protein and calmodulin: analysis of complex formation and solution structure.
Majava V, Petoukhov MV, Hayashi N, Pirila P, Svergun DI, Kursula P.BMC Struct Biol. 2008 Feb 19;8:10.
- 3.
- Repetitive DNA (TGGA)n 5' to the human myelin basic protein gene: a new form of oligonucleotide repetitive sequence showing length polymorphism.
Boylan KB, Ayres TM, Popko B, Takahashi N, Hood LE, Prusiner SB.Genomics. 1990 Jan;6(1):16-22.
- Entrez GeneID:
- 4155
- Protein Accession#:
- NP_001020272;P02686
- Gene Name:
- MBP
- Gene Alias:
- MGC99675
- Gene Description:
- myelin basic protein
- Omim ID:
- 159430
- Gene Ontology:
- Hyperlink
- Gene Summary:
- The protein encoded by the classic MBP gene is a major constituent of the myelin sheath of oligodendrocytes and Schwann cells in the nervous system. However, MBP-related transcripts are also present in the bone marrow and the immune system. These mRNAs arise from the long MBP gene (otherwise called "Golli-MBP") that contains 3 additional exons located upstream of the classic MBP exons. Alternative splicing from the Golli and the MBP transcription start sites gives rise to 2 sets of MBP-related transcripts and gene products. The Golli mRNAs contain 3 exons unique to Golli-MBP, spliced in-frame to 1 or more MBP exons. They encode hybrid proteins that have N-terminal Golli aa sequence linked to MBP aa sequence. The second family of transcripts contain only MBP exons and produce the well characterized myelin basic proteins. This complex gene structure is conserved among species suggesting that the MBP transcription unit is an integral part of the Golli transcription unit and that this arrangement is important for the function and/or regulation of these genes. [provided by RefSeq
- Other Designations:
- Golli-mbp,OTTHUMP00000174383,OTTHUMP00000174384,OTTHUMP00000174385,OTTHUMP00000174386
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