ARHGDIB monoclonal antibody, clone 97A1015
产品名称： ARHGDIB monoclonal antibody, clone 97A1015
英文名称： ARHGDIB monoclonal antibody, clone 97A1015
产品编号： MAB0059
产品价格： null
产品产地： 台湾
品牌商标： Abnova
更新时间： null
使用范围：
亚诺法生技股份有限公司（Abnova)
- 联系人 :
- 地址 : 台湾台北市内湖区洲子街 108 号 9 楼
- 邮编 : 11493
- 所在区域 : 台湾
- 电话 : +886-920**1152 点击查看
- 传真 : 点击查看
- 邮箱 : sales@abnova.com.tw
- Specification
- Product Description:
- Mouse monoclonal antibody raised against synthetic peptide of ARHGDIB.
- Immunogen:
- A synthetic peptide corresponding to the region of the Fas-induced cleavage site of human ARHGDIB.
- Host:
- Mouse
- Reactivity:
- Human, Mouse
- Form:
- Liquid
- Isotype:
- IgG2b
- Storage Buffer:
- In PBS (0.05% BSA, 0.05% sodium azide)
- Storage Instruction:
- Store at 4°C. For long term storage store at -20°C.
Aliquot to avoid repeated freezing and thawing.
- Recommend Usage:
- The optimal working dilution should be determined by the end user.
- Note:
- This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
- Publication Reference
- 1.
- Pseudomonas aeruginosa-induced human mast cell apoptosis is associated with up-regulation of endogenous Bcl-xS and down-regulation of Bcl-xL.
Jenkins CE, Swiatoniowski A, Power MR, Lin TJ.J Immunol. 2006 Dec 1;177(11):8000-7.
- 2.
- Pseudomonas aeruginosa exotoxin A induces human mast cell apoptosis by a caspase-8 and -3-dependent mechanism.
Jenkins CE, Swiatoniowski A, Issekutz AC, Lin TJ.J Biol Chem. 2004 Aug 27;279(35):37201-7. Epub 2004 Jun 17.
- 3.
- Mitochondrial DNA mutation and depletion increase the susceptibility of human cells to apoptosis.
Liu CY, Lee CF, Hong CH, Wei YH.Ann N Y Acad Sci. 2004 Apr;1011:133-45.
- 4.
- Hydroxylation at C4' or C6 is essential for apoptosis-inducing activity of flavanone through activation of the caspase-3 cascade and production of reactive oxygen species.
Ko CH, Shen SC, Chen YC.Free Radic Biol Med. 2004 Apr 1;36(7):897-910.
- 5.
- Rutinoside at C7 attenuates the apoptosis-inducing activity of flavonoids.
Chen YC, Shen SC, Lin HY.Biochem Pharmacol. 2003 Oct 1;66(7):1139-50.
- Applications
- Western Blot (Cell lysate)
- Western blot analysis of ARHGDIB in Jurkat cells using ARHGDIB monoclonal antibody, clone 10D774 (Cat # MAB0058) at 2 ug/mL and ARHGDIB monoclonal antibody, clone 97A1015 (Cat # MAB0059) at 0.1 ug/mL. Cells were treated with 2 uM staurosporine for different time periods. ARHGDIB monoclonal antibody, clone 10D774 (Cat # MAB0058) detects both the full-length and cleaved forms of ARHGDIB while ARHGDIB monoclonal antibody, clone 97A1015 (Cat # MAB0059) specifically detects only the cleaved form of the protein.
- Immunohistochemistry (Formalin/PFA-fixed paraffin-embedded sections)
- Immunohistochemical analysis of ARHGDIB monoclonal antibody, clone 97A1015 (Cat # MAB0059) in formalin-fixed, paraffin-embedded human breast tumor tissue using an isotype control (top) and ARHGDIB monoclonal antibody, clone 97A1015 (Cat # MAB0059) (bottom) at 5 ug/mL .
- Gene Pathway